Codeine Phosphate For IBS

About Codeine Phosphate. Drug information on this anti-diarrheal drug.

General Information

Indications

IBS (Unlicensed in UK), Chronic diarrhoea, Analgesia (Pain relief)

Other drug names

Diarrest, Kaodene, Codeine

Cautions

May cause drowsiness - avoid driving or operating machinery in this situation. Can cause abdominal distension.

Contraindications

Acute diarrhoea conditions such as acute inflammatory colitis or antibiotic associated colitis.

side effects

Nausea, vomiting, constipation, drowsiness, low blood pressure

Adult dose

Codeine 30mg three to four times a day (range 15mg to 60mg)

Codeine Formulations

Tablets, Codeine syrup, Liquid combination preparations

PLEASE NOTE: Whilst this website has taken every care to make sure the information is correct, I cannot accept any liability for any of the above information. If any concerns, always read the drug manufacturers guidelines or consult a doctor.

The Doctors View

Codeine Phosphate is particularly good in the treatment of diarrhea. It has the qualities of both reducing diarrhea and also has an analgesic effect when cramps are an issue. It can cause drowsiness so should be used with caution, but is a good drug to use when symptoms are bad.

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The References:

1) Double-blind cross-over study comparing loperamide, codeine and diphenoxylate in the treatment of chronic diarrhea. Palmer KR, Corbett CL, Holdsworth CD. Gastroenterology. 1980 Dec;79(6):1272-5.

2) Loperamide, diphenoxylate, and codeine in chronic diarrhoea. Shee CD, Pounder RE. Br Med J. 1980 Feb 23;280(6213):524